Susanne Brix

This study identifies NAD metabolism as a sex-dependent factor influencing early-life infection outcomes, showing sex-specific effects of NAD precursor supplementation in mice and humans.

This study shows that inhibiting glycolysis or supplementing ketones can reduce inflammation and improve outcomes in neonatal sepsis by enhancing mitochondrial metabolism and disease tolerance.

The paper investigates how dual utilization of human milk oligosaccharides and dietary fibers influences gut microbiome selection during weaning.

The paper shows that boosting TCA cycle activity through nutritional strategies improves neonatal host defense against infection by enhancing disease tolerance and resistance.

The paper updates a software tool to generate single-cell spatial gene expression profiles using cell boundary images from Stereo-seq data, showing improved performance on mouse liver and Arabidopsis seed datasets.

CellBin processes high-resolution spatial transcriptomics data to generate accurate single-cell gene expression profiles, improving accuracy and efficiency in mouse brain tissue analysis.

This paper performs M-GWAS on a Chinese cohort to identify genetic contributions to the gut microbiome and its associations with complex diseases.

The paper uses single-cell RNA-seq to study liver and gallbladder development from the embryonic endoderm, identifying key transcription factors and gene expression changes during differentiation.