Ole Bæk

This study identifies NAD metabolism as a sex-dependent factor influencing early-life infection outcomes, showing sex-specific effects of NAD precursor supplementation in mice and humans.

This study shows that reducing glucose supply in preterm infants with infection reduces pulmonary damage and metabolic disturbances.

This study integrates spatiotemporal data from skin and blood to reveal BCG-induced molecular networks and predictive biomarkers of vaccine response.

This study shows that inhibiting glycolysis or supplementing ketones can reduce inflammation and improve outcomes in neonatal sepsis by enhancing mitochondrial metabolism and disease tolerance.

The paper shows that boosting TCA cycle activity through nutritional strategies improves neonatal host defense against infection by enhancing disease tolerance and resistance.

This study shows that reducing glucose supply in infected preterm pigs decreases neurological and renal damage by modulating innate and Th1 immunity.

This study compares metabolic and defense strategies in preterm piglets infected with S. epidermidis, finding that survivors exhibit early resistance and later tolerance, linked to mitochondrial metabolism and improved survival.