Duc Ninh Nguyen

This study identifies NAD metabolism as a sex-dependent factor influencing early-life infection outcomes, showing sex-specific effects of NAD precursor supplementation in mice and humans.

This study shows that reducing glucose supply in preterm infants with infection reduces pulmonary damage and metabolic disturbances.

This study shows that inhibiting glycolysis or supplementing ketones can reduce inflammation and improve outcomes in neonatal sepsis by enhancing mitochondrial metabolism and disease tolerance.

This study shows that active donor virome in fecal filtrate transfer reduces NEC severity in preterm piglets, while inactivated virome abolishes these protective effects.

This study investigates INH-induced hepatotoxicity, showing ER stress inhibition can mitigate oxidative stress and mitochondrial dysfunction during early exposure.

This study shows that reducing glucose supply in infected preterm pigs decreases neurological and renal damage by modulating innate and Th1 immunity.

This study compares metabolic and defense strategies in preterm piglets infected with S. epidermidis, finding that survivors exhibit early resistance and later tolerance, linked to mitochondrial metabolism and improved survival.

The paper identifies blood transcriptomic markers of necrotizing enterocolitis (NEC) in preterm pigs, showing up-regulation of PAK2 and other genes associated with NEC severity and bacterial infection.