Björn Klabunde

This study shows that reducing glucose supply in preterm infants with infection reduces pulmonary damage and metabolic disturbances.

This study shows that inhibiting glycolysis or supplementing ketones can reduce inflammation and improve outcomes in neonatal sepsis by enhancing mitochondrial metabolism and disease tolerance.

The paper shows that boosting TCA cycle activity through nutritional strategies improves neonatal host defense against infection by enhancing disease tolerance and resistance.

This study compares metabolic and defense strategies in preterm piglets infected with S. epidermidis, finding that survivors exhibit early resistance and later tolerance, linked to mitochondrial metabolism and improved survival.

Autoencoder design plus a roughly 24-hour cell-free screen tested 500 candidates over five rounds, finding 30 functional AMPs; six were broad-spectrum with no resistance emerging in E. coli.