Anna Hammerich Thysen

NAD metabolism mediates a sex-specific protection against early life infections

This study identifies NAD metabolism as a sex-dependent factor influencing early-life infection outcomes, showing sex-specific effects of NAD precursor supplementation in mice and humans.

Ketone and glycolytic metabolism are key modulators of inflammation during neonatal sepsis

This study shows that inhibiting glycolysis or supplementing ketones can reduce inflammation and improve outcomes in neonatal sepsis by enhancing mitochondrial metabolism and disease tolerance.

Harnessing systemic glycolysis-TCA cycle axis to boost the host defense against newborn infection

The paper shows that boosting TCA cycle activity through nutritional strategies improves neonatal host defense against infection by enhancing disease tolerance and resistance.