Bo Chawes

This study identifies NAD metabolism as a sex-dependent factor influencing early-life infection outcomes, showing sex-specific effects of NAD precursor supplementation in mice and humans.

This study shows that inhibiting glycolysis or supplementing ketones can reduce inflammation and improve outcomes in neonatal sepsis by enhancing mitochondrial metabolism and disease tolerance.

The paper shows that boosting TCA cycle activity through nutritional strategies improves neonatal host defense against infection by enhancing disease tolerance and resistance.

This study uses multiway data analysis to characterize postprandial metabolic responses in humans, revealing BMI-related differences in metabolite groups and temporal profiles between males.

The paper uses metabolomics and machine learning to identify metabolites associated with early childhood hs-CRP levels, finding 52 metabolites with potential bioactivity linked to systemic inflammation.

This study evaluates CP models for analyzing postprandial metabolomics data through simulations, showing their effectiveness in revealing metabolic patterns and group differences.