Asifa Akhtar

This study shows BRD2 clustering on acetylated chromatin is critical for RNA Polymerase II recruitment and transcription initiation.

The paper develops a scaffolding algorithm using Hi-C data to assemble chromosome-length genomes in Drosophila species, revealing conserved 3D regulatory topologies despite extensive genome shuffling.

This study shows the NSL complex maintains nucleosome organization at promoters, ensuring transcription fidelity and suppressing noise by preventing nucleosome invasion into NDRs.

The paper introduces uvCLAP, a non-radioactive method for identifying in vivo RNA-binding protein targets, showing it is reliable and comparable to other methods.

The paper identifies DNA motifs at TAD boundaries in flies and shows they encode 3D genome architecture, with an online database for exploration.

The paper analyzes the evolutionary dynamics of roX lncRNAs and their genomic occupancy across species, revealing structural repeats and binding site turnover.