Claudia Isabelle Keller Valsecchi

This study maps how heat-stress effects are transmitted through zebrafish generations, showing persistent maternal RNA signatures and transient offspring phenotypes.

This study identifies PAIP1 as a cofactor for mRNA export and shows it couples nuclear to cytoplasmic mRNP remodeling and poly(A) homeostasis, affecting mRNA stability and development.

The paper shows SNRPN, a paralogue of SNRPB, stabilizes metabolic transcripts and enhances mitochondrial function, revealing a methylation-dependent mechanism for metabolic specialization in mammals.

This study maps sex-specific transcriptome dynamics in Anopheles gambiae embryos, revealing early sex-biased gene expression and dosage compensation mechanisms.

The paper investigates epigenetic regulation in the Colorado potato beetle, which lacks DNMT3, revealing that CpG methylation and H3K36me3 correlate with gene expression despite the absence of DNMT3.

This study identifies convergent evolution of H4K16ac-mediated dosage compensation in a ZW species and links it to sex-dependent lifespan differences.

The paper evaluates AlphaFold-Multimer for predicting protein interaction interfaces using short linear motifs and validates some predictions experimentally.

The paper develops a scaffolding algorithm using Hi-C data to assemble chromosome-length genomes in Drosophila species, revealing conserved 3D regulatory topologies despite extensive genome shuffling.