Ho‐Ryun Chung

The paper quantifies enhancer activity dynamics in mESCs during differentiation using FAIRE-STARR-seq, identifying features that predict enhancer activity and reveal regulatory insights.

This study identifies mechanisms by which androgen and glucocorticoid receptors achieve functional diversification through distinct DNA binding and downstream regulatory events.

EPIGENE identifies genome-wide transcription units using histone modifications, outperforming RNA-seq methods and discovering novel TUs supported by RNA Polymerase II data.

CRUP predicts condition-specific regulatory units by analyzing histone modification ChIP-seq data and linking enhancers to target genes in rheumatoid arthritis.

This study shows the NSL complex maintains nucleosome organization at promoters, ensuring transcription fidelity and suppressing noise by preventing nucleosome invasion into NDRs.

normR normalizes ChIP-seq data to improve enrichment calling in different histone modification regimes.