Emanuela Zuccaro

This study investigates how the 22q11.2 deletion affects gene expression in neural progenitor cells and neurons, linking it to schizophrenia risk through altered presynaptic gene products.

The paper identifies human-specific enrichment of schizophrenia risk genes in callosal neurons of the developing neocortex using comparative transcriptomic analysis across species and developmental stages.

FIN-Seq enables transcriptional profiling of specific cell types in frozen human CNS tissues using immunolabeled nuclei sequencing.

This study shows polyglutamine-expanded androgen receptor disrupts muscle function by altering calcium dynamics and excitation-contraction coupling gene expression, which can be reversed by treatment.