Author

Yiyi Yan

Mayo ClinicORCID 0000-0001-8981-4702Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

Haidong DongiD· 2 shared Sean S. ParkiD· 2 shared Aaron S. Mansfiled· 1 shared Aaron Scott MansfieldiD· 1 shared Aubrey Y. Liew· 1 shared Chunhua Chen· 1 shared Eugene D. Kwon· 1 shared Kun Ling· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

Haidong DongORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 25, 2026

Integrative AI-Enabled Virtual Cell Modeling Reveals a Clinically Relevant Latent Effector State of Human CD8 T Cells Undetectable by Conventional Analyses

Ying Li, Mojun Zhu, Roxana Stefania Dronca…·Haidong Dong

The paper uses AI to model CD8 T-cell responses during ICI therapy, identifying a latent effector state that conventional methods miss.

DOI 10.64898/2026.07.22.739582

𝕏 PostBluesky

Cancer BiologybioRxivPreprintApr 25, 2018

B7-H1(PD-L1) confers chemoresistance through ERK and p38 MAPK pathway in tumor cells

Xiaosheng Wu, Yanli Li, Xin Liu…·Haidong Dong

This study shows B7-H1(PD-L1) promotes chemoresistance in tumor cells via ERK pathway activation and reduces it via p38 MAPK pathway activation when B7-H1 is deficient.

DOI 10.1101/308601

humanproteomics

𝕏 PostBluesky