Author

Sean S. Park

Mayo ClinicORCID 0000-0003-3814-853XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1

Frequent Co-Authors

Haidong DongiD· 2 shared Yiyi YaniD· 2 shared Aaron S. Mansfiled· 1 shared Aaron Scott MansfieldiD· 1 shared Abhishek ChandraiD· 1 shared Aqsa Komel· 1 shared Aubrey Y. Liew· 1 shared Chunhua Chen· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersImmunology

Haidong DongORCID

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Author profile →

3 papers

Recent·Most cited

Cancer BiologyJournal of Bone and Mineral ResearchPeer-reviewedAug 7, 2026

Suppression of early pro-inflammatory senescent signature post-radiotherapy mitigates chronic bone damage

David Achudhan, Jacob J. Orme, Ritika Sharma…·Abhishek Chandra

This study shows that early suppression of the pro-inflammatory senescent secretome (SASP) with ruxolitinib reduces chronic bone damage after radiotherapy.

DOI 10.1093/jbmr/zjag122

mousehuman

𝕏 PostBluesky

ImmunologybioRxivPreprintJul 25, 2026

Integrative AI-Enabled Virtual Cell Modeling Reveals a Clinically Relevant Latent Effector State of Human CD8 T Cells Undetectable by Conventional Analyses

Ying Li, Mojun Zhu, Roxana Stefania Dronca…·Haidong Dong

The paper uses AI to model CD8 T-cell responses during ICI therapy, identifying a latent effector state that conventional methods miss.

DOI 10.64898/2026.07.22.739582

humanscRNA-seq

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Cancer BiologybioRxivPreprintApr 25, 2018

B7-H1(PD-L1) confers chemoresistance through ERK and p38 MAPK pathway in tumor cells

Xiaosheng Wu, Yanli Li, Xin Liu…·Haidong Dong

This study shows B7-H1(PD-L1) promotes chemoresistance in tumor cells via ERK pathway activation and reduces it via p38 MAPK pathway activation when B7-H1 is deficient.

DOI 10.1101/308601

humanproteomics

𝕏 PostBluesky