Molecular BiologyNature Structural & Molecular BiologyPeer-reviewed
Spatially clustered piRNA genes promote the transcription of piRNAs via condensate formation of the H3K27me3 reader UAD-2
Chengming Zhu, Xiaoyue Si, Xinhao Hou…·Shouhong Guang
The paper shows that spatial clustering of piRNA genes in nematodes enhances transcription through phase separation involving UAD-2 and the SUMO regulatory factors GEI-17 and TOFU-3.
10 citationstop 5%