GWAS of epigenetic ageing rates in blood reveals a critical role for TERT
Ake Tzu-Hui Lu, Luting Xue, Elias Salfati, Brian H. Chen, Luigi Ferrucci, Daniel A Levy, Roby Joehanes, Joanne M. Murabito, Douglas P. Kiel, Pei-Chien Tsai, İdil Yet, Jordana T. Bell, Massimo Mangino, Toshiko Tanaka, Allan F. McRae, , Steve Horvath
This study identifies genetic variants associated with epigenetic age acceleration and shows TERT's role in regulating the DNA methylation clock.
bioRxiv · Jun 30, 2017 · PreprintGenetics