Author

Degisew Yinur Mengistu

Sapienza University of RomeORCID 0000-0001-9086-132XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Laura CiapponiiD· 2 shared Maria Patrizia SommaiD· 2 shared Marta MarzulloiD· 2 shared Marta TerribiliiD· 2 shared Assia De Simone· 1 shared Claudia PellacaniiD· 1 shared Emma Montivero Morales· 1 shared Gianluca CanettieriiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersGenetics

Laura CiapponiORCID

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2 papers

Recent·Most cited

GeneticsDisease Models & MechanismsPeer-reviewedApr 20, 2026

Distinct Cellular Effects of Myotonic Dystrophy type 2 RAN Tetrapeptides in Drosophila melanogaster

Marta Marzullo, Assia De Simone, Marta Terribili…·Laura Ciapponi

This study investigates the distinct toxic effects of QAGR and PACL peptides in Drosophila, showing they impair nucleolar function and autophagy or alter stress granule dynamics, contributing to DM2 pathogenesis.

DOI 10.1242/dmm.052729

Drosophilaproteomics

𝕏 PostBluesky

GeneticsbioRxivPreprintJul 22, 2025

Microcephaly-Associated Genes asp and Sas4 Control Chromatin Organization and Nuclear Lamina Structure in Drosophila melanogaster

Degisew Yinur Mengistu, Marta Marzullo, Claudia Pellacani…·Laura Ciapponi

This study shows that asp and Sas4 genes in Drosophila affect nuclear structure, chromatin organization, and genome stability, contributing to microcephaly pathogenesis.

DOI 10.1101/2025.07.22.666102

DrosophilaChIP-seq

𝕏 PostBluesky