Author

Claudia Pellacani

Institute of Molecular Biology and PathologyORCID 0000-0002-6818-1229Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Laura CiapponiiD· 2 shared Marta MarzulloiD· 2 shared Degisew Yinur MengistuiD· 1 shared Emma Montivero Morales· 1 shared Fabian M. FeiguiniD· 1 shared Federico Riccardi· 1 shared Giulia RomanoiD· 1 shared Marcella MarchettiiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenetics

Laura CiapponiORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintJul 22, 2025

Microcephaly-Associated Genes asp and Sas4 Control Chromatin Organization and Nuclear Lamina Structure in Drosophila melanogaster

Degisew Yinur Mengistu, Marta Marzullo, Claudia Pellacani…·Laura Ciapponi

This study shows that asp and Sas4 genes in Drosophila affect nuclear structure, chromatin organization, and genome stability, contributing to microcephaly pathogenesis.

DOI 10.1101/2025.07.22.666102

DrosophilaChIP-seq

𝕏 PostBluesky

Molecular BiologyCell Death DiscoveryPeer-reviewedSep 27, 2023

Su(var)3-9 mediates age-dependent increase in H3K9 methylation on TDP-43 promoter triggering neurodegeneration

Marta Marzullo, Giulia Romano, Claudia Pellacani…·Fabian M. Feiguin

The paper shows that Su(var)3-9 increases H3K9 methylation on the TDP-43 promoter with age, leading to reduced TDP-43 expression and neurodegeneration in Drosophila, mice, and humans.

10 citations

Drosophilamouse

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