Author

Said A Mansour

Hamad bin Khalifa UniversityORCID 0000-0001-9091-4276Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Janarthanan PonrajiD· 3 shared Houda Yasmine Ali MoussaiD· 2 shared Kyung Chul ShiniD· 2 shared Yongsoo ParkiD· 2 shared Angela PyleiD· 1 shared Annabelle E. Hartanto· 1 shared Daniel ErskineiD· 1 shared Jack P. BainesiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersNeuroscience

Janarthanan PonrajORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 9, 2024

Seed-competent alpha-synuclein pathology in metachromatic leukodystrophy: the expanding spectrum of alpha-synucleinopathy in sphingolipidoses

Simona S. Ghanem, Jade I. Hawksworth, Searlait Thom…·Daniel Erskine

This study examines alpha-synuclein pathology in metachromatic leukodystrophy (MLD) brain tissue, finding seed-competent alpha-synuclein conformers in juvenile-onset cases, similar to Lewy body diseases.

3 citations

humanprotein structure

𝕏 PostBluesky

NeurosciencebioRxivPreprintMay 28, 2023

PIP2 electrostatically triggers vesicle fusion: arresting full SNARE assembly and vesicle fusion by PIP2-masking

Houda Yasmine Ali Moussa, Kyung Chul Shin, Janarthanan Ponraj…·Yongsoo Park

The paper shows that MARCKS masks PIP2, arresting SNARE assembly and vesicle fusion, while PIP2 unmasking by Ca2+/CaM or PKC-epsilon rescues fusion and enhances synaptotagmin-1 activity.

DOI 10.1101/2023.05.28.542642

experimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 3, 2022

Requirement of cholesterol for calcium-dependent vesicle fusion by stabilizing synaptotagmin-1-induced membrane bending

Houda Yasmine Ali Moussa, Kyung Chul Shin, Janarthanan Ponraj…·Yongsoo Park

This study shows cholesterol is required for Ca2+-dependent vesicle fusion by stabilizing synaptotagmin-1-induced membrane bending.

DOI 10.1101/2022.02.03.478933

experimental assay

𝕏 PostBluesky