Author

Giovana da Costa Venancio

University of Virginia Medical CenterORCID 0000-0001-9130-2482Unclaimed ORCID profile · follow to get notified of new preprints

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Arati K. SharmaiD· 1 shared B. Bishal PaudeliD· 1 shared Bhavishya U. Ramamoorthy· 1 shared Charles Edward ChalfantiD· 1 shared David F. ClaxtoniD· 1 shared David J. FeithiD· 1 shared Francine E. Garrett-BakelmaniD· 1 shared Irene Sung-Ah Lee· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Arati K. SharmaORCID

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1 paper

Recent·Most cited

Acid ceramidase inhibition enhances BCL-2 targeting in venetoclax-resistant acute myeloid leukemia via a cytotoxic integrated stress response

Johnson Ung, Su‐Fern Tan, Jeremy J.P. Shaw, Maansi Taori, Tess M. Deddens, Giovana da Costa Venancio, McLane M. Montgomery, James T. Hagen, Raphael Taiwo Aruleba, Upendarrao Golla, Arati K. Sharma, B. Bishal Paudel, Irene Sung-Ah Lee, Bhavishya U. Ramamoorthy, Kevin A. Janes, , Thomas P. Loughran

This study shows that inhibiting acid ceramidase (AC) enhances venetoclax's effectiveness in venetoclax-resistant AML by inducing a cytotoxic integrated stress response.

bioRxiv · Jun 6, 2025 · PreprintCancer Biology