Helder C. Ferreira

This study shows that XNP-1, the C. elegans homologue of ATRX, maintains cellular identity by preventing ectopic germline gene expression, and its loss leads to developmental defects.

The paper shows that POT-3 binds the telomeric G-overhang and has distinct sequence selectivity compared to POT-2.

This study shows that Uls1, an ATP-dependent chromatin remodelling enzyme, prevents Top2 poisoning in yeast by altering Top2 chromatin binding and reducing Top2 accumulation at tRNA genes after drug treatment.

The paper presents structures of yeast Chd1 bound to a ubiquitinylated nucleosome, revealing how it interacts with DNA and histone modifications.