Author

Minhong Huang

Iowa State UniversityORCID 0000-0001-9159-6484Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Anumantha G. KanthasamyiD· 2 shared Arthi KanthasamyiD· 2 shared Huajun JiniD· 2 shared Vellareddy AnantharamiD· 2 shared Adhithiya Charli· 1 shared Canan G. NebigiliD· 1 shared Dan Wen LouiD· 1 shared Dehui Kong· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPharmacology & Toxicology

Anumantha G. KanthasamyORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Prokineticin-2 Upregulates GDNF in Astrocytes and Pharmacological Modulation of PK2 Receptors offers Neuroprotection in Experimental Models of Parkinson's Disease

Jie Denny Luo, Griffin Clabaugh, Matthew P Neal, Minhong Huang, Souvarish Sarkar, Gary D. Zenitsky, Huajun Jin, Vellareddy Anantharam, Canan G. Nebigil, Laurent Désaubry, Arthi Kanthasamy, Anumantha G. Kanthasamy

This study shows that PK2 signaling increases GDNF in astrocytes and that modulating PK2 receptors protects neurons in Parkinson's disease models.

bioRxiv · Sep 8, 2025 · PreprintPharmacology & Toxicology

Mitochondrial Dysfunction Induces Epigenetic Dysregulation by H3K27 Hyperacetylation to Perturb Active Enhancers in Parkinson’s Disease Models

Minhong Huang, Dan Wen Lou, Adhithiya Charli, Dehui Kong, Huajun Jin, Vellareddy Anantharam, Arthi Kanthasamy, Zhibin Wang, Anumantha G. Kanthasamy

This study shows that mitochondrial dysfunction in Parkinson’s disease models leads to H3K27 hyperacetylation, disrupting active enhancers and epigenetic regulation.

bioRxiv · Oct 17, 2019 · PreprintNeuroscience