Mengting Liu

The paper identifies two fungal P450 enzymes that catalyze oxidative demethylation of prenyl groups to form allenes and alkynes in natural products.

This study characterizes the biosynthesis of E-64, a cysteine protease inhibitor, and demonstrates its biocatalytic potential for generating potent analogs.

This paper combines MicroED and native mass spectrometry to determine structures of enzyme-inhibitor complexes and identify high-affinity ligands from crude samples.