Author

Joern Huelsmeier

Trinity College DublinORCID 0000-0001-9209-5251Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 3 Research Focus:cell-cell communication· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Baskar BakthavachaluiD· 3 shared Mani RamaswamiiD· 3 shared Amanjot SinghiD· 2 shared Arnas PetrauskasiD· 2 shared Arvind Reddy KandiiD· 2 shared Jens Hillebrand· 2 shared Khushboo AgrawaliD· 2 shared Sai Shruti PothapragadaiD· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Baskar BakthavachaluORCID

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3 papers

Recent·Most cited

NeurosciencePLoS GeneticsPeer-reviewedMay 20, 2024

Structured and disordered regions of Ataxin-2 contribute differently to the specificity and efficiency of mRNP granule formation.

Arnas Petrauskas, Daniel L. Fortunati, Amanjot Singh…·Baskar Bakthavachalu

This study investigates how structured and disordered regions of Ataxin-2 influence mRNP granule formation and neurodegeneration in Drosophila and human models.

14 citations

Drosophilahuman

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NeurosciencebioRxivPreprintOct 1, 2021

Ataxin-2 Disordered Region Promote Huntingtin Protein Aggregation And Neurodegeneration In Drosophila Models Of Huntington's Disease.

Joern Huelsmeier, Emily Walker, Baskar Bakthavachalu, Mani Ramaswami

This study shows that the Ataxin-2 disordered region promotes Huntingtin protein aggregation and neurodegeneration in Drosophila HD models.

1 citation

Drosophilaexperimental assay

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NeuroscienceeLifePeer-reviewedMar 10, 2021

ANTAGONISTIC ROLES FOR ATAXIN-2 STRUCTURED AND DISORDEREDDOMAINS IN RNP CONDENSATION

Amanjot Singh, Joern Huelsmeier, Arvind Reddy Kandi…·Baskar Bakthavachalu

This study identifies Ataxin-2 target mRNAs and shows its structured and disordered domains regulate RNP granule formation and mRNA stability in Drosophila.

33 citations

Drosophilamultiome

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