Author

Arvind Reddy Kandi

Goethe University FrankfurtORCID 0000-0002-4020-1769Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Organism:Drosophila· 2 Organism:mouse· 2 Research Focus:protein structure prediction· 2 Research Focus:differential expression· 1

Frequent Co-Authors

Georg W. J. AuburgeriD· 3 shared Amanjot SinghiD· 2 shared Arnas PetrauskasiD· 2 shared Baskar BakthavachaluiD· 2 shared Jana KeyiD· 2 shared Jens Hillebrand· 2 shared Joern HuelsmeieriD· 2 shared Khushboo AgrawaliD· 2 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersMolecular Biology

Georg W. J. AuburgerORCID

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4 papers

Recent·Most cited

ATXN2L primarily interacts with NUFIP2, the absence of ATXN2L results in NUFIP2 depletion, and the ATXN2-polyQ expansion triggers NUFIP2 accumulation

Jana Key, Luis Enrique Almaguer-Mederos, Arvind Reddy Kandi, Nesli-Ece Şen, Suzana Gispert, Gabriele Koepf, David Meierhofer, Georg W. J. Auburger

This study identifies ATXN2L interactors and shows that its absence leads to NUFIP2 depletion, while ATXN2-polyQ expansion causes NUFIP2 accumulation.

Neurobiology of Disease · Apr 11, 2025Peer-reviewedMolecular Biology

Spinal cord phosphoproteome of a SCA2/ALS13 mouse model reveals alteration of ATXN2-N-term SH3-actin interactome and of autophagy via WNK1-MYO6-OPTN-SQSTM1

Luis Enrique Almaguer-Mederos, Arvind Reddy Kandi, Nesli-Ece Şen, Júlia Canet-Pons, Luca-Malena Berger, Jana Key, Melinda Elaine Brunstein, Christian Münch, Suzana Gispert, Georg W. J. Auburger

The paper analyzes the phosphoproteome and interactome of a SCA2/ALS13 mouse model to identify altered signaling and protein interactions linked to neurodegeneration.

bioRxiv · Nov 6, 2024 · PreprintMolecular Biology

Structured and disordered regions of Ataxin-2 contribute differently to the specificity and efficiency of mRNP granule formation.

Arnas Petrauskas, Daniel L. Fortunati, Amanjot Singh, Arvind Reddy Kandi, Sai Shruti Pothapragada, Khushboo Agrawal, Joern Huelsmeier, Jens Hillebrand, Georgia Brown, Dhananjay Chaturvedi, Jongbo Lee, Chunghun Lim, Georg W. J. Auburger, K. VijayRaghavan, Mani Ramaswami, Baskar Bakthavachalu

This study investigates how structured and disordered regions of Ataxin-2 influence mRNP granule formation and neurodegeneration in Drosophila and human models.

PLoS Genetics · May 20, 2024Peer-reviewedNeuroscience

ANTAGONISTIC ROLES FOR ATAXIN-2 STRUCTURED AND DISORDEREDDOMAINS IN RNP CONDENSATION

Amanjot Singh, Joern Huelsmeier, Arvind Reddy Kandi, Sai Shruti Pothapragada, Jens Hillebrand, Arnas Petrauskas, Khushboo Agrawal, RT Krishnan, Devasena Thiagarajan, Deepa Jayaprakashappa, Krishnaswamy VijayRaghavan, Mani Ramaswami, Baskar Bakthavachalu

This study identifies Ataxin-2 target mRNAs and shows its structured and disordered domains regulate RNP granule formation and mRNA stability in Drosophila.

eLife · Mar 10, 2021Peer-reviewedNeuroscience