Baskar Bakthavachalu

This study identifies Ataxin-2 as a regulator of the synaptonemal complex in Drosophila, showing its role in chromosome pairing during meiosis.

SMARTIE improves the analysis of RNA editing data to identify and rank RBP target RNAs by integrating statistical tests with confidence-weighted features.

This study identifies Ataxin-2 as a regulator of meiotic entry in Drosophila by downregulating Dacapo, leading to timely premeiotic DNA replication and preventing genomic damage in oocytes.

The paper develops an enzyme-based rRNA-depletion method for Drosophila total RNA, showing improved efficiency and non-coding RNA enrichment compared to commercial kits.

This study investigates how structured and disordered regions of Ataxin-2 influence mRNP granule formation and neurodegeneration in Drosophila and human models.

The paper shows that local axonal translation of CaMKII mRNA, mediated by Mub and a 3UTR element, is essential for asymmetric CaMKII distribution and associative memory in Drosophila neurons.

This study shows that the Ataxin-2 disordered region promotes Huntingtin protein aggregation and neurodegeneration in Drosophila HD models.

This study identifies Ataxin-2 target mRNAs and shows its structured and disordered domains regulate RNP granule formation and mRNA stability in Drosophila.