Author

Jens Hillebrand

Trinity College Dublin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 3 Research Focus:cell-cell communication· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Mani RamaswamiiD· 3 shared Amanjot SinghiD· 2 shared Arnas PetrauskasiD· 2 shared Arvind Reddy KandiiD· 2 shared Baskar BakthavachaluiD· 2 shared Joern HuelsmeieriD· 2 shared Khushboo AgrawaliD· 2 shared Sai Shruti PothapragadaiD· 2 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersNeuroscience

Mani RamaswamiORCID

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3 papers

Recent·Most cited

The Ataxin-2 protein is required in Kenyon cells for RNP-granule assembly and appetitive long-term memory formation.

Camilla Roselli, Jens Hillebrand, Jenifer C Kaldun, Vernon Monteiro, Thomas R. Hurd, Simon G. Sprecher, Tamara Boto, Mani Ramaswami

This study shows Ataxin-2 is required in Kenyon cells for mRNP granule assembly and appetitive long-term memory formation in Drosophila.

Journal of Neurogenetics · Jul 3, 2025Peer-reviewedNeuroscience

Structured and disordered regions of Ataxin-2 contribute differently to the specificity and efficiency of mRNP granule formation.

Arnas Petrauskas, Daniel L. Fortunati, Amanjot Singh, Arvind Reddy Kandi, Sai Shruti Pothapragada, Khushboo Agrawal, Joern Huelsmeier, Jens Hillebrand, Georgia Brown, Dhananjay Chaturvedi, Jongbo Lee, Chunghun Lim, Georg W. J. Auburger, K. VijayRaghavan, Mani Ramaswami, Baskar Bakthavachalu

This study investigates how structured and disordered regions of Ataxin-2 influence mRNP granule formation and neurodegeneration in Drosophila and human models.

PLoS Genetics · May 20, 2024Peer-reviewedNeuroscience

ANTAGONISTIC ROLES FOR ATAXIN-2 STRUCTURED AND DISORDEREDDOMAINS IN RNP CONDENSATION

Amanjot Singh, Joern Huelsmeier, Arvind Reddy Kandi, Sai Shruti Pothapragada, Jens Hillebrand, Arnas Petrauskas, Khushboo Agrawal, RT Krishnan, Devasena Thiagarajan, Deepa Jayaprakashappa, Krishnaswamy VijayRaghavan, Mani Ramaswami, Baskar Bakthavachalu

This study identifies Ataxin-2 target mRNAs and shows its structured and disordered domains regulate RNP granule formation and mRNA stability in Drosophila.

eLife · Mar 10, 2021Peer-reviewedNeuroscience