Juan Du

The paper shows that temperature and Ca2+ alter TRPM4's pharmacology, revealing how these factors influence ligand binding and channel function.

The paper shows mechanical trichome brushing in Arabidopsis increases Cd2+ uptake by inducing stomatal opening through malate-mediated signaling, independent of ABA.

This study investigates the molecular mechanisms of partial agonist action and conformational transitions in the glycine receptor using electrophysiology, MD simulations, and cryo-EM.