Author

Henrike P. Muller

University College LondonORCID 0000-0002-4682-4553Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Courtney HimsworthiD· 2 shared John AndersoniD· 2 shared Amy K Erbe-Gurel· 1 shared Brendan C. McIntyreiD· 1 shared Chantelle E BowersiD· 1 shared Chunlong ZhaoiD· 1 shared Elisavet Kalaitsidou· 1 shared Elizabeth Tucker· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

Courtney HimsworthORCID

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2 papers

Recent·Most cited

CD47 blockade augments anti-GD2 driven phagocytosis in vitro but fails to improve in vivo efficacy in immune competent, chemoresistant neuroblastoma preclinical models

Courtney Himsworth, Thomas John Jackson, Chantelle E Bowers, Sophie Munnings-Tomes, Gaya Nair, Henrike P. Muller, Elizabeth Tucker, Amy K Erbe-Gurel, PaulM. Sondel, Louis Chesler, Robbie Mazjner, John Anderson

This study shows CD47 blockade enhances anti-GD2 phagocytosis in vitro but does not improve in vivo efficacy in neuroblastoma models.

PLoS ONE · Oct 27, 2026Peer-reviewedImmunology

Blocking MIF secretion enhances CAR T-cell efficacy against neuroblastoma

Josephine G. M. Strijker, Guillem Pascual‐Pasto, Grant P. Grothusen, Yannine J. Kalmeijer, Elisavet Kalaitsidou, Chunlong Zhao, Brendan C. McIntyre, Stephanie Matlaga, Lindy L. Visser, Marta Barisa, Courtney Himsworth, Rivani Shah, Henrike P. Muller, Linda G. Schild, Peter G. Hains, , Judith Wienke

This study identifies MIF as a key immunosuppressive factor in neuroblastoma that inhibits CAR T-cell efficacy, showing that blocking MIF enhances T-cell activation and therapeutic potential.

European Journal of Cancer · Jan 27, 2025Peer-reviewedCancer Biology