Hanna Antila

Nitrous oxide modulates cortical activity, wake-sleep oscillations, and produces antidepressant-like effects in mice

This study shows that nitrous oxide increases cortical activity, alters wake-sleep oscillations, and produces antidepressant-like effects in mice, similar to ketamine.

Circuit mechanism underlying fragmented sleep and memory deficits in 16p11.2 deletion mouse model of autism

This study identifies heightened LC-NE neuron activity and altered connectivity as causes of sleep fragmentation and memory deficits in a 16p11.2 deletion ASD mouse model.

Regulation of stress-induced sleep fragmentation by preoptic glutamatergic neurons

This study identifies POA glutamatergic neurons as regulators of stress-induced sleep fragmentation through optogenetic manipulation and calcium activity analysis in mice.

Antidepressant drugs act by directly binding to TRKB neurotrophin receptors

This study identifies a direct binding of antidepressants to TRKB receptors, revealing a mechanism linking molecular interactions to antidepressant effects.

Optical activation of TrkB neurotrophin receptor in mouse ventral hippocampus promotes plasticity and facilitates fear extinction

The paper uses optogenetics to activate TrkB receptors in the ventral hippocampus, enhancing plasticity and improving fear extinction in mice.

Chondroitinase and antidepressants promote plasticity by releasing TRKB from dephosphorylating control of PTPσ in parvalbumin neurons

This study shows that chondroitinase and antidepressants promote plasticity in the adult visual cortex by enhancing TRKB signaling in parvalbumin neurons through inhibition of PTPσ.

Isoflurane produces antidepressant effects and induces TrkB signaling in rodents

This study shows that isoflurane anesthesia produces antidepressant-like effects in rodents by activating TrkB signaling and related molecular pathways.