Author

Piia Kohtala

University of HelsinkiORCID 0000-0002-3946-9194Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:electronic health records· 1

Frequent Co-Authors

Samuel KohtalaiD· 2 shared Anders Bue KleiniD· 1 shared Conor M. ListoniD· 1 shared Francis S. LeeiD· 1 shared Gemma González-HernándeziD· 1 shared Hanna AntilaiD· 1 shared Heidi Kaastrup MülleriD· 1 shared Iman BaramakiiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Samuel KohtalaORCID

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2 papers

Recent·Most cited

Nitrous oxide modulates cortical activity, wake-sleep oscillations, and produces antidepressant-like effects in mice

Samuel Kohtala, Puja K. Parekh, Iman Baramaki, Piia Kohtala, Liisa Ilkka, Hanna Antila, Francis S. Lee, Conor M. Liston

This study shows that nitrous oxide increases cortical activity, alters wake-sleep oscillations, and produces antidepressant-like effects in mice, similar to ketamine.

bioRxiv · Feb 13, 2025 · PreprintNeuroscience

Physiological basis underlying antidepressant-induced activation of TrkB receptors

Okko Alitalo, Samuel Kohtala, Marko Rosenholm, Piia Kohtala, Roosa Saarreharju, Nobuaki Matsui, Gemma González-Hernández, Heidi Kaastrup Müller, Wiebke Theilmann, Mirkka P. Sarparanta, Anders Bue Klein, Olli K. Kärkkäinen, Stanislav V. Rozov, Tomi Rantamäki

This study shows that antidepressants activate TrkB receptors through physiological changes like hypothermia and reduced energy expenditure, not just pharmacological action.

bioRxiv · Aug 30, 2021 · PreprintNeuroscience