Author

Mihaela Peycheva

Austrian Academy of SciencesORCID 0000-0001-9268-0637Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Bioinformatics· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:contrastive learning· 1 Approach:deep learning· 1

Frequent Co-Authors

Daniel MalzliD· 4 shared Rushad PavriiD· 3 shared Mariia NazarovaiD· 2 shared Tobias NeumanniD· 2 shared Ursula E. SchoeberliD· 2 shared Ali RahjoueiiD· 1 shared Anindya DuttaiD· 1 shared Anna HakobyaniD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersMolecular Biology

Daniel MalzlORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Specific origin selection and excess functional MCM2-7 loading in ORC-deficient cells.

Yoshiyuki Shibata, Mihaela Peycheva, Etsuko Shibata, Daniel Malzl, Rushad Pavri, Anindya Dutta

The paper shows that specific DNA replication origins are still used and excess MCM2-7 is loaded in ORC-deficient human cancer cells.

Nucleic Acids Research · May 30, 2025Peer-reviewedMolecular Biology

Multimodal learning of transcriptomes and text enables interactive single-cell RNA-seq data exploration with natural-language chats

Moritz Schaefer, Peter Peneder, Daniel Malzl, Mihaela Peycheva, Jake Burton, Anna Hakobyan, Varun S. Sharma, Thomas Krausgruber, Jörg Menche, Eleni M. Tomazou, Christoph Bock

CellWhisperer enables chat-based exploration of single-cell RNA-seq data using natural language by connecting transcriptomes with text through multimodal learning.

bioRxiv · Oct 15, 2024 · PreprintBioinformatics

RIF1 regulates replication origin activity and early replication timing in B cells

Daniel Malzl, Mihaela Peycheva, Ali Rahjouei, Stefano Gnan, Kyle N. Klein, Mariia Nazarova, Ursula E. Schoeberl, David M. Gilbert, Sara B.C. Buonomo, Michela Di Virgilio, Tobias Neumann, Rushad Pavri

This study shows RIF1 regulates early replication timing and origin activity in B cells by interacting with MCM proteins, influencing gene replication without major effects on gene expression or genome organization.

Nature Communications · Dec 11, 2023Peer-reviewedGenetics

DNA replication timing directly regulates the frequency of oncogenic chromosomal translocations

Mihaela Peycheva, Tobias Neumann, Daniel Malzl, Mariia Nazarova, Ursula E. Schoeberl, Rushad Pavri

This study shows DNA replication timing regulates oncogenic chromosomal translocations by affecting DSB ligation, independent of DSB frequency.

Science · Sep 15, 2022Peer-reviewedMolecular Biology