Michela Di Virgilio

This study shows RIF1 regulates early replication timing and origin activity in B cells by interacting with MCM proteins, influencing gene replication without major effects on gene expression or genome organization.

This study identifies phosphorylation of RIF1's intrinsically disordered region as essential for protecting nascent DNA at stalled replication forks during replication stress.

This study shows SURF1 mutations impair human neurogenesis by generating patient-derived iPS cells and demonstrating defects in neuronal differentiation and bioenergetics.