Author

Rachel A. DeWeerd

Washington University in St. LouisORCID 0000-0001-9309-113XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Abby M. GreeniD· 2 shared Brooke R. Harris· 2 shared Dylan F. FingermaniD· 2 shared Jeffrey J. BednarskiiD· 2 shared Alessandro VindigniiD· 1 shared Alice MeroniiD· 1 shared Ava R. HanseniD· 1 shared Danielle LaVigne· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersCancer Biology

Abby M. GreenORCID

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2 papers

Recent·Most cited

Cancer BiologyJCI InsightPeer-reviewedMar 9, 2025

APOBEC3A drives metastasis of ovarian cancer by altering epithelial-to-mesenchymal transition

Jessica Merritt Devenport, Thi Tran, Brooke R. Harris…·Abby M. Green

This study shows APOBEC3A promotes ovarian cancer metastasis by altering epithelial-to-mesenchymal transition in high-grade serous ovarian cancer.

7 citationstop 5%

humanwhole-genome sequencing

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Molecular BiologybioRxivPreprintNov 28, 2023

The SMC5/6 complex is required for maintenance of genome integrity upon APOBEC3A-mediated replication stress

David R O’Leary, Ava R. Hansen, Dylan F. Fingerman…·Abby M. Green

This study identifies the SMC5/6 complex as essential for genome stability in cells with active APOBEC3A, showing that its loss leads to increased DNA damage and replication stress.

DOI 10.1101/2023.11.28.568952

humanexperimental assay

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