Jens Reiners

This study shows that the catalytic activity of Ubp3, a yeast deubiquitinase, is independent of its interaction partner Bre5, challenging the current model of Bre5-dependent activation.

This study investigates the conformational dynamics of the membrane-anchored foldase LipH and shows how it recognizes, folds, and releases its client lipase LipA.

The paper identifies and structures MpTACO1, a dual-targeted protein in plants, showing its role in enhancing translation of mitochondrial and plastid-encoded proteins.

The paper introduces ATPLyzer, a ratiometric biosensor for monitoring ATP dynamics, showing its utility in E. coli and demonstrating growth-phase and carbon-supply-dependent ATP changes.

The paper introduces CoBiSe, a computational method for biosensor design, and demonstrates its application in creating IronSenseR, a biosensor for ferrous iron with high specificity and sensitivity.

The paper presents the first complete structural model of the HlyA T1SS using cryo-EM and SAXS, revealing CLD domain dynamics and toxin binding mechanisms.

The paper determines the structure of crTPpart2 from two chromatophore-targeted proteins, revealing a fold similar to γ-glutamyl-cyclotransferase and suggesting its role in protein import.

This study identifies Jps1 as a key protein facilitating unconventional secretion in Ustilago maydis by interacting with phosphoinositides, revealing its structural and functional roles in Cts1 export.

The paper determines the crystal structure of Bep1, revealing a novel FIC-OB-BAS(BID) domain arrangement and its role in T4SS translocation.