Author

Vickie H. Y. Wong

The University of MelbourneORCID 0000-0001-9356-7556Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Bang Viet BuiiD· 2 shared Guei‐Sheung LiuiD· 2 shared Jiang-Hui WangiD· 2 shared Alex William HewittiD· 1 shared Alice PébayiD· 1 shared Anai Gonzalez-CorderoiD· 1 shared Anna Elizabeth KingiD· 1 shared Anthony L. CookiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMolecular Biology

Bang Viet BuiORCID

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2 papers

Recent·Most cited

Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedOct 30, 2024

Characterisation of RNA editing and gene therapy with a compact CRISPR-Cas13 in the retina

Satheesh Kumar, Yi-Wen Hsiao, Vickie H. Y. Wong…·Guei‐Sheung Liu

This study characterizes the transcriptomic effects of Cas13bt3 in retinal cells and demonstrates its efficacy in silencing VEGFA mRNA in human retinal organoids and mouse models.

19 citations

humanmouse

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GeneticsHuman Gene TherapyPeer-reviewedAug 2, 2019

Efficacy and dynamics of self-targeting CRISPR/Cas constructs for gene editing in the retina.

Li Fan, Sandy S. C. Hung, Mohd Khairul Nizam Mohd Khalid…·Guei‐Sheung Liu

This study develops a self-destructing CRISPR/Cas system for retinal gene editing, showing reduced SpCas9 mRNA and improved safety without compromising on-target efficiency.

24 citations

mouseCRISPR screen

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