Cancer BiologybioRxiv
Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer
Fei Yue, Amy Tsu Ku, Payton D. Stevens…·Yi Li
The paper shows that ZNRF3/RNF43 ubiquitinates and degrades EGFR, and their loss increases EGFR signaling, promoting cancer growth.
3 citations