Author
University of CambridgeORCID 0000-0001-9410-9805Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Sheenagh Aiken, Daniele Fiorito, Matthew Harper…·A. Sofia F. Oliveira
This paper identifies critical receptor-ligand interactions that distinguish varenicline from other nAChR agonists, revealing unique hydrogen bonding interactions essential for its function.
Uriel López-Sánchez, Lachlan Jake Munro, Lucy Kate Ladefoged…·Anders S. Kristensen
This study investigates how vortioxetine interacts with human and rodent 5-HT3 receptors, revealing structural differences and mechanisms of action.
Marijke Brams, Cédric Govaerts, Kumiko Kambara…·Chris Ulens
The paper identifies a conserved vestibule binding site in pLGICs and shows nanobodies can act as allosteric modulators, expanding drug design possibilities.