Author

Sarah Lynn Ondrejka

Cleveland ClinicORCID 0000-0001-9431-2889Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron D. VinyiD· 1 shared Alexander Fisher· 1 shared Anabella Maria D. GalangiD· 1 shared Besmira Alija· 1 shared Claudia GebhardiD· 1 shared Edna Stewart· 1 shared Eno-obong Udoh· 1 shared Govind BhagatiD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Aaron D. VinyORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintApr 1, 2025

Altered chromatin accessibility mediated by somatic cohesin mutations amplifies FLI1-Menin output to promote leukemogenesis

Jane Jialu Xu, Viviana Scoca, Yi Chen…·Aaron D. Viny

This study shows that cohesin mutations alter chromatin accessibility, enhancing FLI1-Menin interaction and promoting leukemogenesis through therapeutic vulnerabilities.

DOI 10.1101/2025.04.01.646632

humanChIP-seq

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