Author

Edna Stewart

Columbia University Irving Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron D. VinyiD· 1 shared Alexander Fisher· 1 shared Anabella Maria D. GalangiD· 1 shared Besmira Alija· 1 shared Claudia GebhardiD· 1 shared Eno-obong Udoh· 1 shared Govind BhagatiD· 1 shared Jane Jialu XuiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Aaron D. VinyORCID

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1 paper

Recent·Most cited

Altered chromatin accessibility mediated by somatic cohesin mutations amplifies FLI1-Menin output to promote leukemogenesis

Jane Jialu Xu, Viviana Scoca, Yi Chen, Yingqian Ada Zhan, Alexander Fisher, Eno-obong Udoh, Sebastian Fernando, Besmira Alija, John Pantazi, Varun S. Sudunagunta, Edna Stewart, Anabella Maria D. Galang, Michael Williams, Govind Bhagat, Claudia Gebhard, , Aaron D. Viny

This study shows that cohesin mutations alter chromatin accessibility, enhancing FLI1-Menin interaction and promoting leukemogenesis through therapeutic vulnerabilities.

bioRxiv · Apr 1, 2025 · PreprintCancer Biology