Soichiro Kakuta

This study identifies LUBEL/RNF31 as a key regulator of T-tubule biogenesis through linear ubiquitination, showing its interaction with Amphiphysin and role in membrane tubulation.

This study shows that ubiquilin-2 droplets catalyze α-synuclein fibril formation in vitro and in cells, and identifies a compound that inhibits this process.

This paper develops a multi-scale neuronal imaging technique combining light and electron microscopy with a tissue clearing method to study brain-wide connectivity across multiple spatial scales.