Author

Wilhelmus Josephus Kwanten

University of AntwerpORCID 0000-0001-9474-6695Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Ashwin Srinivasan KumariD· 1 shared Dai FukumuraiD· 1 shared Dan Gabriel DudaiD· 1 shared David H. EbbiD· 1 shared Hye-Jung KimiD· 1 shared Landry BlanciD· 1 shared Lei XuiD· 1 shared Mark A. Duquette· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ashwin Srinivasan KumarORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

Targeting Tumor-derived Sphingosine Kinase 2 Unleashes Antitumor Immunity and Improves Survival of Mice with Group 3 Medulloblastoma

Sampurna Chatterjee, Pragya Kumar, Ashwin Srinivasan Kumar, Pin‐Ji Lei, Meenal Datta, Yuhui Zhao, William W. Ho, Nilesh P. Talele, Patrik Andersson, Mark A. Duquette, Shuji Kitahara, Landry Blanc, Samantha J. Wong, Wilhelmus Josephus Kwanten, David H. Ebb, , Rakesh K. Jain

This study identifies SPHK2 as a therapeutic target in G3MB, showing that its inhibition restores anti-tumor immunity and improves survival in mouse models, with enhanced effects when combined with radiation.

bioRxiv · Aug 14, 2026 · PreprintCancer Biology