William W. Ho

This study identifies SPHK2 as a therapeutic target in G3MB, showing that its inhibition restores anti-tumor immunity and improves survival in mouse models, with enhanced effects when combined with radiation.

This study shows mutant p53R172H in pancreatic cancer enhances immunosuppressive chemokine Cxcl1 expression via enhancer activation, reducing immune checkpoint inhibitor efficacy.

This study shows that combining anti-PD1 treatment with radiation therapy for vestibular schwannomas improves tumor control, reduces radiation dose, and elicits systemic anti-tumor effects.

This study identifies IL-6 and EGFR signaling as therapeutic targets for schwannomatosis, showing combined blockade reduces both pain and tumor growth in preclinical models.