Jacob M. Allen

This study shows social stress worsens colitis via beta-adrenergic and NADPH oxidase-driven oxidative stress, with beta-blockers and apocynin reducing inflammation.

This paper uses meta-analysis and machine learning to show plant-protein diets increase gut microbial diversity and specific taxa, while animal-protein diets favor proteolytic taxa and different metabolic pathways.

This study optimizes a PROTAC to degrade IDO1 with high potency in GBM cells, showing sustained degradation via the ubiquitin-proteasome system.

This study investigates how influenza A virus infection during pregnancy affects maternal intestinal immunity and fetal brain development, finding dose-dependent effects without increased IL-17 signaling.

This study shows that aging alters gut microbiota immunogenicity, increasing TLR4 activation and inflammation, and that these changes are linked to heightened host inflammation.