Cancer BiologybioRxivPreprint
Diphenyleneiodonium chloride inhibits MYCN-amplified neuroblastoma by targeting MYCN induced mitochondrial alterations
Soraya Epp, Stephanie Maher, Amirah Adlina Abdul Aziz…·Melinda Halász
This study identifies diphenyleneiodonium chloride as a compound that targets MYCN-amplified neuroblastoma by inducing proteasomal degradation of MYCN and reversing mitochondrial alterations.