MYCN inhibits TrkC-mediated differentiation in neuroblastoma cells via disruption of the PKA signalling pathway
Stephanie Maher, Andrew Roe, Kieran J. Wynne, Vadim Zhernovkov, Melinda Halász
This study shows MYCN inhibits TrkC-induced differentiation in neuroblastoma by disrupting PKA signaling, with implications for targeting PKA to treat high-risk cases.
Cell Death Discovery · Mar 25, 2026Peer-reviewedCancer Biology