Author

Jordy Sepulveda

Georgetown UniversityORCID 0000-0001-9529-6761Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Adrian LitaiD· 1 shared Alan CieslukowskiiD· 1 shared Alexandra G. BeilinaiD· 1 shared Christian A. CombsiD· 1 shared Darwin D’souzaiD· 1 shared Dimitrios KleidonasiD· 1 shared Dolores HambardzumyaniD· 1 shared Dominic J. AcriiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Adrian LitaORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 27, 2026

Genetic drivers shape TREM2-dependent myeloid responses and glioblastoma progression

Mekenzie Peshoff, Tanvi Joshi, Darwin D’souza…·Long‐Jun Wu

This study shows TREM2's role in glioblastoma depends on genetic context and timing, with different effects in Nf1-silenced/Ras-driven and PDGFB-driven models.

DOI 10.64898/2026.10.26.759860

mousebulk RNA-seq

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Cell BiologyCell ReportsPeer-reviewedJul 1, 2025

Triglyceride metabolism controls inflammation and APOE4-associated disease states in microglia

Roxan A. Stephenson, Jordy Sepulveda, Kory R. Johnson…·Priyanka S. Narayan

This study shows that triglyceride metabolism is essential for microglial activation and disease states in APOE4 microglia, with implications for modulating immune responses.

59 citationstop 1%

humanbulk RNA-seq

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