Sphingosine kinase 2 suppresses neutrophil responses to promote viral persistence while attenuating immune pathology
Vijayamahantesh Vijayamahantesh, Ying He, Lei Jiang…·Bumsuk Hahm
This study shows that SphK2 deficiency in neutrophils reduces immune suppression, enhances T cell responses, and decreases viral persistence during LCMV infection.