Author

Rory Doolan

Swiss Tropical and Public Health InstituteORCID 0000-0001-9592-7607Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Dovran OvezgeldiyeviD· 3 shared Tiffany BoucheryiD· 3 shared Vanessa TrefzeriD· 3 shared Alexander SerraiD· 2 shared Nicola Laraine HarrisiD· 2 shared Shirin RezaeiiD· 2 shared Alana ButleriD· 1 shared Alexander SmithiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersImmunology

Dovran OvezgeldiyevORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Holding glycolysis in check though Alox15 activity is required for macrophage M2 commitment and function in tissue repair and anti-helminth immunity.

Dovran Ovezgeldiyev, Vanessa Trefzer, Rory Doolan, Mati Moyat, Gillian Coakley, Lakshanie C. Wickramasinghe, Carmel Daunt, Beatrice Volpe, Fiona D. R. Henkel, Alexander Serra, Maike Hartmann, Shirin Rezaei, Niki D. J. Ubags, Alana Butler, Roxanne Chatzis, , Tiffany Bouchery

The Journal of Experimental Medicine · Aug 18, 2026Peer-reviewedImmunology

Natural microbial exposure imposes layered constraints on epithelial and type 2 immunity

Dovran Ovezgeldiyev, Rory Doolan, Vanessa Trefzer, Alina Baltensperger, Shirin Rezaei, Alexander Serra, Christina Pohl, Namitha Putananickal, Betina Chalethu, Elad kuku, Julian Dommann, Pierre Schneeberger, Solveig Runge, Vanessa Lang, Christina Gmeiner, , Tiffany Bouchery

The study shows that natural microbial exposure reduces tuft cell responsiveness in mice, affecting type 2 immunity and helminth resistance compared to sterile conditions.

bioRxiv · May 7, 2026 · PreprintImmunology

Screening of the Pathogen box reveals novel anti blood-feeding compounds

Dovran Ovezgeldiyev, Rory Doolan, Vanessa Trefzer, Carmel P. Daunt, Melisa Altindag, Joyce van Bree, Nicola Laraine Harris, Tiffany Bouchery

This study screens compounds from the MMV Pathogen Box against a rodent hookworm model to identify anti-blood-feeding agents, finding five compounds effective in vitro and well-tolerated in vivo.

bioRxiv · Aug 25, 2025 · PreprintMicrobiology