Author

Alexander Smith

Baker Heart and Diabetes InstituteORCID 0000-0003-4593-3042Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Alexander Smith1 paper

Biology Disciplines

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Developmental Biology· 1 Genetic & Genomic Medicine· 1 Genomics· 1 Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

Corey GilesiD· 2 shared Kevin HuynhiD· 2 shared Peter J. MeikleiD· 2 shared Adaikalavan RamasamyiD· 1 shared Adriano BiasiniiD· 1 shared Alana ButleriD· 1 shared Alexander SerraiD· 1 shared Amir AriffiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Corey GilesORCID

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5 papers

Recent·Most cited

ImmunologyThe Journal of Experimental MedicinePeer-reviewedAug 18, 2026

Holding glycolysis in check though Alox15 activity is required for macrophage M2 commitment and function in tissue repair and anti-helminth immunity.

Dovran Ovezgeldiyev, Vanessa Trefzer, Rory Doolan…·Tiffany Bouchery

1 citation

mousebulk RNA-seq

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Developmental BiologyThe EMBO JournalPeer-reviewedJan 23, 2023

The Grainyhead/LSF transcription factor GRH-1 is rhythmically required for molting

Milou W.M. Meeuse, Yannick P. Hauser, Smita Nahar…·Helge Großhans

The paper identifies GRH-1 as a transcription factor essential for rhythmic molting in C. elegans, showing its role in gene regulation and cuticle formation.

23 citations

C. elegansChIP-seq

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Genetic & Genomic MedicineNature CommunicationsPeer-reviewedJun 6, 2022

Comprehensive genetic analysis of the human lipidome identifies novel loci controlling lipid homeostasis with links to coronary artery disease

Gemma Cadby, Corey Giles, Phillip E. Melton…·Eric Keith Moses

This study identifies 667 genetic loci associated with lipid species and links 186 of them to coronary artery disease through integrative lipidomics and genomics.

107 citations

humanbulk RNA-seq

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Systems BiologybioRxivPreprintApr 23, 2021

Developmental and Intergenerational Landscape of Human Circulatory Lipidome and its Association with Obesity Risk

Sartaj Ahmad Mir, Li Chen, Satvika Burugupalli…·Neerja Karnani

The paper maps the developmental and intergenerational changes in the human circulatory lipidome and identifies lipid signatures associated with obesity risk in mothers and offspring.

2 citations

humanmetabolomics

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GenomicsiSciencePeer-reviewedJun 20, 2020

The contribution of lincRNAs at the interface between cell cycle regulation and cell state maintenance

Adriano Biasini, Alexander Smith, Baroj Abdulkarim…·Ana Claudia Marques

The paper identifies cell cycle-associated lincRNAs in mouse embryonic stem cells and shows their role in cell cycle regulation and pluripotency maintenance.

4 citations

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