Xudong Wu

This study identifies a paracrine-to-autocrine GREM1 signaling shunt in colorectal cancer that promotes metastasis via ACVR1C, highlighting a mechanism of signaling autonomy in advanced stages.

This paper shows that KDM2B suppresses Wnt signaling in neural progenitors to regulate hippocampal development and morphology.

This paper develops an inducible CRISPRi system in mouse embryonic stem cells and generates a knockin mouse model for gene function studies.

This study identifies LncKdm2b as a lncRNA that cis-activates Kdm2b to regulate cortical neuronal differentiation through chromatin remodeling.