Author

Bo Zhao

Brigham and Women's HospitalORCID 0000-0002-2163-6484Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Bo Zhao2 papers · Brigham and Women's Hospital

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Microbiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Niu WangiD· 2 shared Alex K. ShalekiD· 1 shared Ankit Basak· 1 shared Baochun ZhangiD· 1 shared Benjamin E. GewurziD· 1 shared Berkay ŞímșekiD· 1 shared Bokai ZhuiD· 1 shared Brooke E. HowittiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersBiochemistry

Niu WangORCID

Author profile →

4 papers

Recent·Most cited

LTBP isoforms differentially encode TGF-β spatial localization and activation

Lixia Wang, Dong Zhou, Jie Tan, Xuezhen Lin, Xinyu Zhao, Pengqing Yuan, Jizhe Liu, Ruxue Li, Niu Wang, Ziying Wang, Fu‐Ying Tian, Ying Li, Zhe Zhang, Bo Zhao

The paper investigates how different LTBP isoforms regulate TGF-β spatial localization and activation through structural and functional analyses.

bioRxiv · Aug 6, 2026 · PreprintBiochemistry

A Paracrine-to-Autocrine Shunt of GREM1 Fuels Colorectal Cancer Metastasis via ACVR1C

Huaixiang Zhou, Qunlong Jin, Zhang Fu, Yanming Yang, Yunfei Gao, Niu Wang, Bo Zhao, Long Gui, Jiang Li, Zijing Zhu, Ying Zhang, YULONG HE, Shouqing Luo, Li Fu, Xudong Wu, , Ningning Li

This study identifies a paracrine-to-autocrine GREM1 signaling shunt in colorectal cancer that promotes metastasis via ACVR1C, highlighting a mechanism of signaling autonomy in advanced stages.

Molecular Cancer · Jan 24, 2026Peer-reviewedCancer Biology

Epstein-Barr Virus Encoded lncRNAs Control the Viral Lytic Switch

Zhi‐Xuan Li, Yifei Liao, Weiyue Ding, Davide Maestri, Scott L. Grote, Gabriel A. Romero Agosto, Laura A. Murray‐Nerger, Rui Guo, Bo Zhao, Silvi Rouskin, Mingxiang Teng, Benjamin E. Gewurz

This study identifies viral lncRNAs that regulate EBV reactivation by interacting with CTCF and modulating enhancer-promoter looping.

bioRxiv · Oct 29, 2025 · PreprintMicrobiology

Same-Slide Spatial Multi-Omics Integration Reveals Tumor Virus-Linked Spatial Reorganization of the Tumor Microenvironment

Yao Yu Yeo, Yuzhou Chang, Huaying Qiu, Stephanie Pei Tung Yiu, Hendrik A. Michel, Wenrui Wu, Xiaojie Jin, Shoko Kure, Lindsay K. Parmelee, Shuli Luo, Precious Cramer, Jia Le Lee, Yang Wang, Jason Yeung, Nourhan El Ahmar, , Sizun Jiang

This paper introduces IN-DEPTH and SGCC for spatial multi-omics analysis, revealing EBV-related immunomodulatory differences in DLBCL.

bioRxiv · Dec 20, 2024 · PreprintSystems Biology